Jan Bakker Selected Research

Wounds and Injuries (Trauma)

3/2013	Single-nucleotide polymorphisms in the Toll-like receptor pathway increase susceptibility to infections in severely injured trauma patients.
9/2011	Near-infrared spectroscopy for monitoring peripheral tissue perfusion in critically ill patients.

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Jan Bakker Research Topics

Disease

36	Critical Illness (Critically Ill) 01/2024 - 01/2007
34	Septic Shock (Toxic Shock Syndrome) 04/2024 - 01/2004
32	Shock 03/2024 - 01/2004
19	Sepsis (Septicemia) 01/2021 - 06/2003
11	COVID-19 12/2022 - 08/2020
8	Hyperlactatemia 03/2024 - 09/2010
8	Hypotension (Low Blood Pressure) 11/2023 - 01/2008
8	Hypoxia (Hypoxemia) 11/2023 - 04/2008
7	Infections 01/2021 - 08/2004
7	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 01/2011
6	Hemorrhage 01/2022 - 10/2007
4	Cardiogenic Shock 03/2024 - 01/2019
4	Delirium 01/2023 - 10/2014
3	Heart Arrest (Cardiac Arrest) 11/2023 - 02/2014
3	Respiratory Insufficiency (Respiratory Failure) 03/2021 - 01/2021
3	Endotoxemia 01/2020 - 05/2004
3	Brain Death (Brain Dead) 06/2011 - 02/2010
2	Ischemia 03/2024 - 12/2014
2	Hyperemia 01/2024 - 01/2023
2	Tachycardia (Tachyarrhythmias) 11/2023 - 01/2015
2	Out-of-Hospital Cardiac Arrest 11/2023 - 08/2012
2	Respiratory Tract Infections (Respiratory Tract Infection) 10/2021 - 04/2014
2	Heart Failure 01/2021 - 01/2019
2	Inflammation (Inflammations) 01/2021 - 12/2020
2	Lactic Acidosis 01/2021 - 05/2013
2	Brain Ischemia (Cerebral Ischemia) 02/2020 - 05/2016
2	Acidosis 01/2020 - 05/2013
2	Hypovolemia 08/2017 - 01/2015
2	Ventilator-Associated Pneumonia 12/2014 - 08/2011
2	Wounds and Injuries (Trauma) 03/2013 - 09/2011
1	Hypothermia 03/2024
1	Pulmonary Embolism 03/2024
1	Communicable Diseases (Infectious Diseases) 01/2022
1	Low Cardiac Output 01/2021
1	Patient-Ventilator Asynchrony 01/2021
1	Reperfusion Injury 01/2021
1	Hypercapnia 09/2020
1	Right Ventricular Dysfunction 09/2020
1	Deglutition Disorders (Dysphagia) 03/2020
1	Malnutrition (Nutritional Deficiencies) 03/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Obesity 01/2020
1	Hemorrhagic Shock 11/2019
1	Bradycardia 10/2019
1	Brain Injuries (Brain Injury) 09/2019
1	Hypertension (High Blood Pressure) 01/2019

Drug/Important Bio-Agent (IBA)

40	Lactic Acid (Lactate)FDA LinkGeneric 03/2024 - 01/2008
8	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2024 - 12/2013
6	Oxygen (Dioxygen)IBA 01/2021 - 04/2008
5	Biomarkers (Surrogate Marker)IBA 11/2023 - 04/2012
4	Lipocalin-2IBA 11/2019 - 12/2010
3	Nitroglycerin (Dynamite)FDA LinkGeneric 12/2023 - 06/2014
3	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 01/2021 - 02/2020
3	Hypnotics and Sedatives (Sedatives)IBA 01/2020 - 01/2008
2	Carbon DioxideIBA 03/2024 - 01/2023
2	LipopolysaccharidesIBA 01/2023 - 05/2004
2	Topotecan (Hycamtin)FDA LinkGeneric 01/2021 - 12/2020
2	AlbuminsIBA 01/2021 - 01/2019
2	Opioid Analgesics (Opioids)IBA 01/2020 - 04/2008
2	CarboxyhemoglobinIBA 01/2020 - 11/2019
2	Carbon MonoxideIBA 01/2020 - 11/2019
2	CreatinineIBA 01/2019 - 04/2012
2	Glucose (Dextrose)FDA LinkGeneric 05/2016 - 01/2004
2	EndotoxinsIBA 01/2016 - 02/2010
2	AcidsIBA 02/2010 - 10/2009
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2004 - 01/2004
1	E-SelectinIBA 11/2023
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 11/2023
1	SolutionsIBA 09/2022
1	pyrrolidin-3-yl-methanesulfonic acid (PMSA)IBA 01/2022
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	Dopamine (Intropin)FDA LinkGeneric 01/2021
1	Dobutamine FDA LinkGeneric 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	CatecholaminesIBA 01/2021
1	Neuromuscular Blocking AgentsIBA 01/2021
1	fibrin fragment D (D-dimer)IBA 09/2020
1	Pyruvic Acid (Pyruvate)IBA 06/2020
1	Midazolam (Versed)FDA LinkGeneric 01/2020
1	Polyethylene (Polythene)IBA 11/2019
1	Starch (Cornstarch)IBA 11/2019
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019

Therapy/Procedure

43	Resuscitation 04/2024 - 01/2008
18	Critical Care (Surgical Intensive Care) 01/2024 - 08/2004
12	Therapeutics 02/2022 - 01/2004
8	Artificial Respiration (Mechanical Ventilation) 12/2022 - 01/2010
7	Length of Stay 01/2022 - 08/2004
3	Cardiopulmonary Resuscitation (CPR) 11/2023 - 01/2021
3	Fluid Therapy (Oral Rehydration Therapy) 11/2022 - 02/2015
3	Extracorporeal Membrane Oxygenation 01/2020 - 09/2019
3	Early Goal-Directed Therapy 07/2018 - 01/2009
3	Mechanical Ventilators (Ventilator) 08/2011 - 04/2008
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 11/2023 - 01/2021
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2023 - 01/2020
2	Noninvasive Ventilation 01/2021 - 03/2014
2	Continuous Renal Replacement Therapy 01/2015 - 12/2010
2	Intravenous Infusions 01/2008 - 01/2004
1	Thrombectomy 03/2024
1	Airway Management 01/2022
1	Tracheostomy 01/2021